Summary contents
Introduction: Cells as macromolecular assemblies 1 Proteins 2 Compartments PART 1: DNA as information 3 Genes are mutable units 4 DNA is the genetic material 5 Nucleic acid structure 6 Isolating the gene PART 2: From gene to protein 7 Messenger RNA 8 Protein synthesis 9 Interpreting the genetic code 10 Protein localization PART 3: Prokaryotic gene expression 11 Transcription 12 The operon 13 Phage strategies PART PART 4: Perpetuation of DNA 14 The replicon 15 DNA replication 16 Restriction and repair 17 Recombination 18 Transposons 19 Retroviruses and retroposons PART 5: The eukaryotic genome 20 DNA biotechnology 21 Genomes 22 Exons and introns 23 Gene numbers 24 Organelle genomes 25 Simple sequence DNA 26 Chromosomes 27 Nucleosomes PART 6: Eukaryotic gene expression 28 Initiation of transcription 29 Regulation of transcription 30 Nuclear splicing 31 Catalytic RNA 32 Rearrangement of DNA 33 Immune diversity PART 7: Cell growth, cancer, and development 34 Protein trafficking 35 Signal transduction 36 Cell cycle and growth regulation 37 Oncogenes and cancer 38 Gradients and cascades Epilogue: Landmark shifts in perspectives |